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Category: Completed Research Forum: FightAIDS@Home Thread: Supercomputer determines HIV capsid structure |
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Thread Status: Active Total posts in this thread: 2
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
New target(s) for FAAH Dr. Perryman?
----------------------------------------http://gizmodo.com/how-a-supercomputer-may-ha...locked-a-way-to-510672032 In all, the HIV capsid requires 216 protein hexagons and 12 protein pentagons to operate arranged exactly as the predictive models said they would be. The new discovery reveals a stunningly versatile protein in p24. The protein itself is identical whether it's shaped into a pentagon or a hexagon, only the attachment sites between p24 proteins varies between shapes.... By exploiting the capsid's structure, researchers theoretically could deliver a molecular padlock that prevents the viral core from opening and the virus from spreading. This discovery could lead to an entirely new suite of treatment alternatives and could finally outpace HIV's ability to rapidly evolve resistance to current enzyme-based medications. [Edit 2 times, last edit by Former Member at Jul 17, 2013 6:53:07 PM] |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Super computer huh!? Fascinating! Looks like something one of our senior citizen ladies might have come up with while hitting the maryjane and crocheting doilies or tea cozies for the annual wctu raffle. Sorry, couldn't resist.
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